PHARMACEUTICAL COMPOSITION, METHOD FOR THE PREPARATION OR EXPANSION OF STEM CELLS, IN VITRO METHOD FOR THE ASSESSMENT OF THE CELL RESPONSE TO A POTENTIALLY THERAPEUTIC COMPOUND.
JOSE LOPEZ BARNEO,RICARDO PARDAL,PATRICIA ORTEGA-SAENZ,ROCIO DURAN,VICTORIA EUGENIA BONILLA HENAO,ANTONIO ORDONEZ FERNANDEZ,JUAN JOSE TOLEDO ARAL
申请号：
BRPI0815007
公开号：
BRPI0815007A2
申请日:
2008.08.01
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
Adult stem cells obtained from the carotid body, characterized in that they are positive for the phenotypic marker GFAP (glial fibrillary acidic protein) and negative for the phenotypic markers TH (tyrosine hydroxylase) and nestin, are described. These stem cells can undergo proliferation, self-renewal and differentiation to progenitor cells and differentiated cells. Said stem cells, progenitor cells and differentiated cells, expanded by any method, can be used in the treatment of neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease.
