Yong Xu,Benjamin G. Brenning,Steven G. Kultgen,Xiaohui Liu,Michael Saunders,Koc-Kan Ho
申请号：
US13187903
公开号：
US20120058997A1
申请日:
2011.07.21
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides protein kinase inhibitors comprising imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine compounds of the following structure (I) and (II):or a stereoisomer, prodrug or pharmaceutically acceptable salt thereof, wherein R, R1, R2 and X are as defined herein. Compositions and methods for using the same in the treatment of cancer and other Pim kinase-associated conditions are also disclosed.
