Provided herein are antibodies or antigen-binding fragments thereof that immunospecifically bind to the fusion (F) protein of Respiratory Syncytial Virus (RSV). Also provided are methods for of prevention, treatment and diagnosis of viral infection and/or the treatment of one more symptoms of RSV-mediated disease. Methods of generating antibodies that immunospecifically bind RSV F protein also are provided.本文提供免疫特異性結合於呼吸道融合性病毒(Respiratory Syncytial Virus,RSV)之融合(F)蛋白的抗體或其抗原結合片段。亦提供預防、治療及診斷病毒感染及/或治療RSV介導性疾病之一或多種症狀的方法。亦提供產生免疫特異性結合RSV F蛋白之抗體的方法。