Sangeeta Chavan,Jacob Levine,Yehuda Tamari,Kevin J. Tracey,Huan Yang
申请号:
US14759681
公开号:
US20150335763A1
申请日:
2014.01.09
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed are therapeutic beads comprising agents, such as nucleic acids, that bind to high mobility group box 1 (HMGB1) and methods of treating subjects with conditions that would benefit from reducing the deleterious effects of HMGB1, such as inflammatory bowel diseases, comprising administering the beads to the gastrointestinal tract of the subjects.