The present invention discloses a method of processing grain with high pressure. The method comprises: mixing the grain and a liquid having specific ingredients in a predetermined weight ratio to obtain a mixture; and applying a pressure of 10-1000 Mpa to the mixture and then drying the mixture to obtain a grain comprising the specific ingredients.本發明揭露一種高壓處理穀類之方法,其包含將穀類與具有特定成分之液體以預定重量比例混和而獲得混和物;以及將混和物以10~1000MPa之壓力處理後乾燥,以獲得具有該特定成分之穀物。