The invention relates to a device (1) for the portioned output of medications (M) from individual chambers (32) of a strip (29) arranged one behind the other which strip comprises a base strip (30) and a closure strip (31) and the raised chambers (32) of which strip can be opened by pressing a handle (53) by sharp edged deflection of the closure strip (31). In order to simplify the design and for safe operation a chamber elevation directed toward the mouthpiece opening (12) blocks the actuation of the handle (53) by means of a blocking element (62) in which position a chamber (32) arranged in front that has already been freed from the closure strip (31) lies above a fall through opening (39) which opening (39) is closed by means of a flap (49) that can be moved into the opening position by the suction air flow.