JEAN-DAMIEN CHARRIER,BENJAMIN JOSEPH LITTLER,YI SHI,JOHN STUDLEY,FRANCOISE YVONNE THEODORA MARIE PIERARD,STEVEN JOHN DURRANT,ROBERT MICHAEL HUGHES,DAVID ANDREW SIESEL,PAUL ANGELL,ARMANDO URBINA
申请号：
PT15151822
公开号：
PT2940017T
申请日:
2012.09.28
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
The present invention relates to processes and intermediates for preparing compounds useful as inhibitors of ATR kinase, such as aminopyrazine-isoxazole derivatives and related molecules. The present invention also relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention； methods of treating of various diseases, disorders, and conditions using the compounds of this invention； processes for preparing the compounds of this invention； intermediates for the preparation of the compounds of this invention； and solid forms of the compounds of this invention. The compounds of this invention have formula I or II: wherein the variables are as defined herein.
