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Azepane inhibitors of menin-MLL interaction
专利权人:
Janssen Pharmaceutica NV
发明人:
Patrick René Angibaud,Vineet Pande,Barbara Herkert,Daniel Jason Krosky,Olivier Alexis Georges Querolle,Aaron Nathaniel Patrick,Isabelle Noëlle Constance Pilatte
申请号:
US16469174
公开号:
US10745409B2
申请日:
2017.12.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to pharmaceutical agents useful for therapy and/or prophylaxis in a mammal, and in particular to azepane compounds, pharmaceutical composition comprising such compounds, and their use as menin/MLL protein/protein interaction inhibitors, useful for treating diseases such as cancer, myelodysplastic syndrome (MDS) and diabetes.
来源网站:
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