PROBLEM TO BE SOLVED: To provide an external preparation comprising urea formulated therein, suppressing a pH rise with time in the preparation and suppressing emission of an ammonia odor.SOLUTION: The external preparation is obtained by formulating the urea and chlorobutanol. The external preparation is prepared by further formulating a buffer. Furthermore, the external preparation is obtained by formulating an amino acid.COPYRIGHT: (C)2007,JPO&INPIT【課題】製剤中の経時的なpH上昇が抑制され、アンモニア臭の発生が抑制された尿素配合外用製剤を提供することを目的とする。【解決手段】尿素及びクロロブタノールを配合することを特徴とする外用製剤。【選択図】 なし
