BOGA, SOBHANA BABU,KELLY, JOSEPH, M.,ZHU, HUGH, Y.,ALHASSAN, ADBUL-BASIT,YAO, XIN,GAO, XIAOLEI,WANG, JAMES J-S,DESAI, JAGDISH, A.,GUDIPATI, SUBRAHMANYAM,LO, SIE-MUN,ZHU, LIANG,COOPER, ALAN, B.,DENG, Y
申请号:
EP11836905
公开号:
EP2632268A4
申请日:
2011.10.24
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Disclosed are the ERK inhibitors of formula (1):and the pharmaceutically acceptable salts thereof, wherein: A is a five membered monocyclic heteroaryl ring; and B is a monocyclic heterocycloalkyl ring, or a monocyclic heterocycloalkenyl ring, or a bridged monocyclic heterocycloalkyl ring, or a fused (monocyclic heterocycloalkyl ring)cyclopropyl ring. Also disclosed are methods of treating cancer using the compounds of formula (1).