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TREATMENT OF PSYCHOLOGICAL CONDITIONS WITH THE USE OF M1-MUSCARINE RECEPTOR ANTAGONISTS
专利权人:
ТЕРАКОС; ИНК. (US)
发明人:
СИД Брайан (US),МЕКЭНИК Джордан (US)
申请号:
RU2012152922/15
公开号:
RU2012152922A
申请日:
2012.12.07
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A method of alleviating the symptoms of depression, which comprises systematically administering to a subject in need thereof a therapeutically effective amount of telenzepine and an antidepressant selected from the group consisting of a selective serotonin reuptake inhibitor (SSRI) and a selective serotonin-norepinephrine reuptake inhibitor (SNRI), in a therapeutically effective amount to reduce symptoms of depression. 2. The method of claim 1, wherein telenzepine is administered systemically. The method of claim 1, wherein the antidepressant is SSRI. The method of claim 3, wherein the SSRI is selected from the group consisting of citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine and sertraline. The method of claim 4, wherein the SSRI is citalopram or escitalopram. The method of claim 4, wherein the SSRI is paroxetine. The method of claim 1, wherein the antidepressant is SNRI. The method of claim 7, wherein the SNRI is selected from the group consisting of milnacipran, mirtazapine, venlafaxine, duloxetine, desvenlafaxine and sibutramine. The method of claim 8, wherein the SNRI is duloxetine. The method of claim 8, wherein the SNRI is desvenlafaxine. A method for treating one or more psychological conditions, which includes the systematic administration to an individual in need of a therapeutically effective amount of one or more selective muscarinic M receptor antagonists (MR-selective), by which one or more psychological conditions are treated. 12. The method of claim 11, wherein one or more psychological conditions are an affective disorder. The method of claim 12, wherein the affective1. Способ уменьшения симптомов депрессии, который включает систематическое введение индивидууму, нуждающемуся в этом, терапевтически эффективного количества телензепина и антидепрессанта, выбранного из группы, состоящей из селективного ингибитора обратного захвата серотонина (SSRI) и селективного ингибитора обратного захвата серотонина-норэпинефрина (SNRI), в терапев
来源网站:
中国工程科技知识中心
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