Michael Block Lazarus;Benjamin J. Gross;Suzanne Walker Kahne
发明人:
Suzanne Walker Kahne,Michael Block Lazarus,Benjamin J. Gross
申请号:
US13375036
公开号:
US20120108605A1
申请日:
2010.06.01
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides inhibitors of O-GIcNAc transferase. Typically, the inhibitors are quinolinone-6-sulfonamides. The invention also provides pharmaceutical compositions thereof and methods for using the same in diabetes and complications thereof, neurodegenerative diseases, cancers, autoimmune diseases, and inflammatory diseases.