YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
发明人:
BEN NERIAH, YINON,BRACHYA, GUY,BURSTAIN, IDO,MINZEL, WALEED,SNIR-ALKALAY, IRIT,VACCA, JOSEPH,LI, DANSU
申请号：
CA2994644
公开号：
CA2994644A1
申请日:
2016.08.04
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or lnterleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.
