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SALES DE UN INHIBIDOR DE PIM QUINASA
专利权人:
INCYTE CORPORATION
发明人:
JIA, Zhongjiang,CAO, Ganfeng,LIN, Qiyan,PAN, Yongchun,QIAO, Lei,SHARIEF, Vaqar,SHI, ChongSheng Eric,XIA, Michael,ZHENG, Changsheng,ZHOU, Jiacheng,LI, Qun
申请号:
PE0003612018
公开号:
PE13372018A1
申请日:
2016.09.09
申请国别(地区):
PE
年份:
2018
代理人:
摘要:
Referring to a hydrated Crystalline Salt of the compound N - (7R) - 4 - [(3R, 4R, 5S) - 3 - amino - 4 - hydroxy - 3 - methylpiperidin-1-yl) - 7 - hydroxy 6,7-dihydro-5h-cyclopenta [b] pyridin-3-yl) - 6 - (2,Difluorofenil) - 5 - 6 - 2 - fluoropyridine - carboxamide, an inhibitor of the PIM Kinases.In addition, it includes Methods of preparation of these intermediaries and its preparation and is useful in the treatment of PIM kinase related diseases such as cancer.Referido a una sal cristalina hidratada del compuesto N-{(7R)-4-[(3R,4R,5S)-3-amino-4-hidroxi-5-metilpiperidin-1-il]-7-hidroxi-6,7-dihidro-5H-ciclopenta[b]piridin-3-il}-6-(2,6-difluorofenil)-5-fluoropiridina-2-carboxamida, un inhibidor de la Pim quinasa. Ademas, incluye metodos de preparacion de estos y los intermediarios en su preparacion y es util en el tratamiento de las enfermedades relacionadas con Pim quinasa tales como cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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