The hemocompatible material has a strong and tight synthetic substrate to which a biological animal tissue such as animal e.g. bovine, pericardium, is adhered by dispersing a substrate constituting material in a solvent. The substrate is made of elastomer such as polyurethane or silicone elastomer. The tissue is treated for several days using a glycol such as polyethyleneglycol, once adhered on the substrate. An independent claim is also included for a method for fabricating a hemocompatible material.본 발명에 따르면, 혈액적합성 물질은 용매에서 기질의 구성 물질의 분산액에 의해 생물학적 조직이 점착되는 강한 누설방지 합성 기질을 포함한다.