INC.;UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION
发明人:
PARKS, GRIFFITH,COPIK, ALICJA,PARKS, GRIFF
申请号：
CA3064897
公开号：
CA3064897A1
申请日:
2018.05.25
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Disclosed are engineered oncolytic viruses, related fusion proteins and polynucleotides encoding them, and methods for treating cancer using the engineered viruses. In one aspect, disclosed herein are engineered oncolytic viruses, wherein the oncolytic virus expresses one or more exogenous membrane bound immune cell targeting ligands comprising an uncleaved signal anchor.
