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SILVER AND GOLD SALTS OF PARTIALLY DEPOLIMERIZED Glycosaminoglycan
专利权人:
КИМФЛЕКСОР; С.Л. (ES)
发明人:
ФЛОРЕС И САЛЬГАДО Франсеск (ES),БЕНИТЕС ХИМЕНЕС Антонио Франсиско (ES),КОСТА И РЬЕРОЛА Маргарита (ES),ФЛОРЕС И КОСТА Рохер (ES),ФЛОРЕС И КОСТА Лайа (ES)
申请号:
RU2014137454
公开号:
RU2014137454A
申请日:
2013.02.15
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A method of producing a salt of partially depolymerized glycosaminoglycan and a metal, where the metal is gold or silver, comprising the following steps: a) depolymerizing a salt of high molecular weight glycosaminoglycan and a metal, where the metal is not gold or silver, with a depolymerizing substance selected from the group consisting of permanganate potassium, sodium hydroxide and hydrogen peroxide; b) discoloration of the product obtained in the previous step with hydrogen peroxide; and c) exchanging metal ions of the product obtained in the preceding step for gold or silver by using a source of gold or silver. 2. The method according to claim 1, which further comprises a step (a ') of depolymerizing the product obtained in step (a) with a depolymerizing substance selected from the group consisting of potassium permanganate, sodium hydroxide and hydrogen peroxide; provided that the depolymerizing substance is different from the substance used in step (a). 3. The method of claim 2, further comprising the step of (a) depolymerizing the product of step (a ') with a depolymerizing substance selected from the group consisting of potassium permanganate, sodium hydroxide and hydrogen peroxide; provided that the depolymerizing substance is different from the substance used in steps (a) and a ') 4. The method according to claim 3, wherein the depolymerizing substance in step (a) is potassium permanganate, the depolymerizing substance in step (a) is sodium hydroxide, and the depolymerizing substance at stage (a ") pre resents a peroxide vodoroda.5. The method of claim 1, wherein the high molecular weight glycosaminoglycan and metal salt of step (a) is selected from the group consisting of sodium salt1. Способ получения соли частично деполимеризованного гликозаминогликана и металла, где металл представляет собой золото или серебро, включающий следующие стадии:a) деполимеризации соли высокомолекулярного гликозаминогликана и металла, где металл не представляет собой зол
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