Warren H. Finlay,Jonathan J. Dennis,Helena Orszanska,Kimberley D. Seed,Karlene Heather Lynch
申请号:
US13131836
公开号:
US08889105B2
申请日:
2009.11.26
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A respirable composition for treatment of a bacterial infection includes one or more active bacteriophages in combination with a pharmaceutically acceptable respirable carrier. The composition includes a carbohydrate carrier, and is prepared as fine powder. In another aspect, bacteriophages are provided in a liquid carrier for administration by nebulization. In one aspect, the bacteriophages have anti-bacterial activity against one or more species or strains of Burkholderia cepacia complex (BCC) bacteria. The invention further relates to the use of a BCC bacteriophage to treat a BCC infection, in particular in an individual suffering from cystic fibrosis.