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Method of stabilizing antibody and stabilized solution-type antibody preparation
专利权人:
Masashi Nakakura;Kyoko Yamauchi;Takashi Kayashita;Yuji Ueno;Atsushi Ishihara
发明人:
Yuji Ueno,Takashi Kayashita,Atsushi Ishihara,Masashi Nakakura,Kyoko Yamauchi
申请号:
US10574016
公开号:
US08496930B2
申请日:
2004.10.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides a method of suppressing the formation of a soluble association of an antibody in a solution; a method of suppressing the formation of a chemically degraded product of an antibody in a solution; and a method of stabilizing an antibody in a solution. The present invention also provides a solution-type antibody preparation in which the formation of a soluble association is suppressed; a solution-type antibody preparation in which the formation of a chemically degraded product is suppressed; a solution-type antibody preparation in which the formation of a soluble association, the formation of a chemically degraded product and the formation of an insoluble aggregate are suppressed; an agent for suppressing the formation of a soluble association of an antibody; an agent for suppressing the formation of a chemically degraded product of an antibody; and a stabilizing agent for an antibody.
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