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Compositions and methods to enhance the immune system
专利权人:
Stichting Sanquin Bloedvoorziening
发明人:
Timo Kars van den Berg
申请号:
US15145365
公开号:
US09920122B2
申请日:
2016.05.03
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to the field of molecular medicine. In particular, it relates to compositions and methods to enhance the clearance of aberrant cells, e.g. cancer cells or virus-infected cells, by the host's immune system. Provided is a composition comprising (i) a therapeutic compound that can trigger a host's immune effector cells against an aberrant cell, such as a therapeutic antibody, and (ii) at least one agent capable of reducing or preventing inhibitory signal transduction initiated via SIRPalpha.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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