PROBLEM TO BE SOLVED: To provide a new pharmaceutical composition containing an immunosuppressant.SOLUTION: There is provided a pharmaceutical composition containing an immunosuppressant, for preventing or alleviating allergic reaction in the treatment of interleukin-6 (IL-6) related diseases using an IL-6 antagonist.【課題】免疫抑制剤を含んで成る新規な医薬組成物。【解決手段】IL-6アンタゴニストによるIL-6関連疾患の治療の際のアレルギー反応の予防又は軽減のための、免疫抑制剤を含んで成る医薬組成物。【選択図】なし