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AGENTS ET PROCEDES
专利权人:
THE UNIVERSITY OF BIRMINGHAM
发明人:
COBBOLD, MARK,MILLAR, DAVID
申请号:
CA2885133
公开号:
CA2885133A1
申请日:
2013.09.17
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The invention provides an agent comprising: (i) a T cell antigen, and (ii) a binding partner for any of CD22, CD23, CD30, CD74, CD70, CD43, CD44, CD47, CD54, CD58, CD62L, CD95, HLA-DR, CD59, CD55, wherein, following binding of the agent to a cell that expresses any of CD22, CD23, CD30, CD74, CD70, CD43, CD44, CD47, CD54, CD58, CD62L, CD95, HLA-DR, CD59, CD55, the agent is internalised and the T cell antigen is presented on the surface of the cell in a form that can be recognised by a T cell.
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