Yi CHEN;Barbara JOYCE-SHAIKH;Merck Sharp &； Dohme Corp.;Holly CHERWINSKI;Daniel CUA;Adele WANG
发明人:
Daniel Cua,Holly Cherwinski,Adele Wang,Yi Chen,Barbara Joyce-Shaikh
申请号：
US16342582
公开号：
US20190241655A1
申请日:
2017.11.06
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides antibodies and antigen-binding fragments thereof that bind ILT3, ILT3 ligand (i.e., PI16) or a complex between ILT3 and the ILT3 ligand. Methods for determining whether ILT3 and the ILT3 ligand bind together or whether a substance agonizes or antagonizes such binding are also provided.
