Queen Mary & Westfield College; University of London
发明人:
Gavin Paul Vinson,John Richard Puddefoot,Stewart Barker
申请号：
US13749180
公开号：
US20130202604A1
申请日:
2013.01.24
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The use of monoclonal antibodies to the angiotensin-II type-I receptor is provided for the treatment of cancer and vascular smooth muscle cell proliferation. Specifically, use is provided of a monoclonal antibody or a fragment thereof to a peptide comprising the N-terminal portion of the angiotensin-II type-1 receptor defined by the sequence(SEQ ID NO: 1) MILNSSTEDG IKRIQDDCPK AGRHNYIFVM IPTLYSIIFV VGIFG in the preparation of a medicament for the treatment of cancer or in the preparation of a medicament for the treatment of vascular smooth muscle (VSM) cell proliferation.
