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p16INK4a Derived Peptides for Prophylaxis and Therapy of HPV-associated Tumors and other p16INK4a Expressing Tumors
专利权人:
Ruprecht-Karls-Universitaet Heidelberg
发明人:
KLOOR, Matthias,REUSCHENBACH, Miriam,VON KNEBEL-DOEBERITZ, Magnus
申请号:
AU2012261781
公开号:
AU2012261781A1
申请日:
2012.12.13
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2012261781A120140703.pdf#####Abstract pl 61NIa derived peptides for prophylaxis and therapy of HPVassociated tumors and other p 1 6 INK4a expressing tumors Described are particular fragments of the cyclin-dependent kinase inhibitor p16 capable of increasing IFN-y secretion of T cells or inducing proliferation of T cells and the use of said fragments for immunizing an individual against HPVassociated or other p1 6 K4 expressing carcinomas, preferably advanced carcinomas.
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