PROBLEM TO BE SOLVED: To provide an ophthalmic composition useful for prevention and amelioration of dry eye symptoms without using any thickening polymer humectant such as hyaluronic acid which may give unsatisfactory usability such as sense of discomfort and unpleasantness when the composition is applied to eyes.SOLUTION: An ophthalmic composition includes: (A) vitamin A (B) an anti-inflammatory component (C) cornea protection component (D) one or more buffers selected from boric acid, borax, and trometamol and (E) an anti-oxidant. The ophthalmic composition has pH of 5.0-7.5.COPYRIGHT: (C)2013,JPO&INPIT【課題】点眼時に違和感や不快感を感じさせるなど、使用性が満足できない場合があるヒアルロン酸等の増粘系の高分子保湿剤を用いなくとも、ドライアイ症状の予防や改善に有用な眼科用組成物の提供。【解決手段】(A)ビタミンA、(B)抗炎症成分、(C)角膜保護成分、(D)ホウ酸、ホウ砂、トロメタモールから選ばれる1種または2種以上の緩衝剤、(E)抗酸化剤を含有し、かつpHを5.0~7.5であることを特徴とする眼科用組成物。【選択図】なし