A composition comprising Polyhydroxyurethanes Glycosaminoglycans hydrolysed glycosaminoglycans glycosamines of glycosaminoglycans chemically modified or not and a Protein or a peptide; said protein being collagen elastin keratin fibronectin actin myosin laminin a peptide or a blend of those proteins or peptides fibrillated hydrolysed chemically modified or not. This homogenous composition is obtained by the polymerisation or the covalent bounding of two preparations containing cyclic polycarbonates polyamines glycosaminoglycans hydrolysed glycosaminoglycans glycosamines chemically modified or not and proteins or peptides or a blend of those proteins or peptides fibrillated hydrolysed chemically modified or not.