The present invention relates to bridged spiro[2.4]heptane derivatives of formula (I),wherein W, Y, Z, R1and R2are as defined in the description, their preparation and their use as pharmaceutically active compounds.本發明係關於式(I)之橋聯螺[2.4]庚烷衍生物,其中W、Y、Z、R1及R2如本說明書中所定義;其製備及其作為醫藥學活性化合物之用途。