JENSEN, MICHAEL, RUGAARD,GARCIA-ECHEVERRIA, CARLOS
申请号:
NZ59289009
公开号:
NZ592890A
申请日:
2009.11.25
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
592890 Disclosed is the use of a compound of formula (E) and an mTOR inhibitor in the manufacture of a medicament for treating a proliferative disease such as tumors, myelomas, leukaemia, angiogenesis, psoriasis, restenosis, sclerodermitis or fibrosis. An example of an mTOR inhibitor is everolimus and an example of a compound of formula (E) is (R)-2-amino-7-[2-(6-methoxy-pyridin-2-yl)-phenyl]-4-methyl-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one.