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HYDROXYDES DE MAGNÉSIUM-FER À DOUBLE COUCHE, LEUR FABRICATION ET LEUR UTILISATION POUR LE TRAITEMENT DE L'HYPERPHOSPHATÉMIE
专利权人:
Opko Ireland Global Holdings; Ltd.
发明人:
申请号:
EP19186506.2
公开号:
EP3611131A1
申请日:
2010.08.02
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
There is provided a method of producing a mixed metal compound comprisingat least Mg2+ and at least Fe3+having an aluminium content of less than 10000 ppm,having an average crystal size of less than 20nm (200A)comprising the steps of:(a) combining a Mg2+ salt and a Fe3+ salt with Na2CO3 and NaOH to produce a slurry, wherein the pH of the slurry is maintained at from 9.5 to 11 , and wherein the Na2CO3 is provided at an excess of 0 to 4.0 moles than is required to complete the reaction(b) subjecting the slurry to mixing under conditions providing a power per unit volume of 0.03 to 1.6kW/m3(c) separating the mixed metal compound from the slurry, to obtain a crude product having a dry solid content of at least 10 wt%(d) drying the crude product either by(i) heating the crude product to a temperature of no greater than 150°C and sufficient to provide a water evaporation rate of 0.05 to 1.5 kg water per hour per kg of dry product, or(ii) exposing the crude product to rapid drying at a water evaporation rate of 500 to 50000 kg water per hour per kg of dry product.
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