ZHANG, Xiaokui,DJURETIC, Ivana,KANG, Lin,VOSKINARIAN-BERSE, Vanessa,STOUT, Bhavani,HARIRI, Robert J.,HOFGARTNER, Wolfgang,EDINGER, James,LAW, Eric,JANKOVIC, Vladimir
申请号:
SG11201803117Y
公开号:
SG11201803117YA
申请日:
2016.10.14
申请国别(地区):
SG
年份:
2018
代理人:
摘要:
Provided herein are methods of producing natural killer (NK) cells and/or ILC3 cells using a three-stage expansion and differentiation method with media comprising stem cell mobilizing factors. Also provided herein are methods of suppressing tumor cell proliferation using the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein, as well as methods of treating individuals having cancer or a viral infection, comprising administering the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein to an individual having the cancer or viral infection.