2-indolinone derivatives as multi-target protein kinase inhibitors and histone deacetylase inhibitors

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专利权人:

Xian-Ping Lu

发明人:

Xian-Ping Lu,Zhi-Bin Li,Zhi-Qiang Ning

申请号：

US12463107

公开号：

US08158656B2

申请日:

2009.05.08

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention relates to 2-indolinone derivatives which are capable of inhibiting protein kinases and histone deacetylases. The compounds of this invention are therefore useful in treating diseases associated with abnormal protein kinase activities or abnormal histone deacetylase activities. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds, and methods of preparing these compounds are also disclosed.

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