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Thrombin mutant
专利权人:
Kazuya Hosokawa
发明人:
Kazuya Hosokawa,Tomoko Wada
申请号:
US12514735
公开号:
US08088372B2
申请日:
2007.11.15
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A thrombin mutant in which at least serine at position 205 among amino acids in the active center of the thrombin B chain has been replaced with another amino acid, and further at least one of the following replacements have been introduced: (I) replacement of arginine at position 89 in the B-chain with another amino acid (II) replacement of threonine at position 69 or serine at position 22 in the B-chain with another amino acid (III) replacement of alanine at position 200 in the B-chain with another amino acid and (IV) replacement of lysine at position 65 in the B-chain with threonine.
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中国工程科技知识中心
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