Disclosed herein are synthetic peptides and compositions comprising the same for the treatment and/or prophylaxis of an ocular disease, particularly, dry eye disease. Also disclosed herein are methods of treating and/or preventing an ocular disease by administering to a subject in need of such treatment a composition containing a synthetic peptide of the present disclosure.在此揭示一種合成胜肽及含所述胜肽的組合物,用以治療和/或預防眼部疾病,特別是乾眼症。本揭示內容亦揭示一種用以治療和/或預防眼部疾病的方法,將含本揭示內容合成胜肽的組合物施用至一有需要的個體。