HUANG, XIANHAI,BRUBAKER, JASON,PETERSON, SCOTT L.,BUTCHER, JOHN W.,CLOSE, JOSHUA T.,MARTINEZ, MICHELLE,MACCOSS, RACHEL NICOLA,JUNG, JOON O.,SILIPHAIVANH, PHIENG,ZHANG, HONGJUN,ASLANIAN, ROBERT G.,BIJU
申请号：
CA2838731
公开号：
CA2838731A1
申请日:
2012.06.14
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters, wherein R1, R2, R7, R8, R8a, E, Y, Z, n, u, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with with uncontrolled or inappropriate stimulation of CRTH2 function.
