Stanley J. Stachelek,Matthew J. Finley,Robert J. Levy
申请号：
US14385890
公开号：
US20150079142A1
申请日:
2013.03.15
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Methods for inhibiting a biomaterial-associated thrombotic event comprise reducing the number of platelets that bind to the biomaterial, or inhibiting platelet activation, by attaching CD47 or the Ig domain thereof to the surface of the biomaterial. Methods of the present invention inhibit thrombi formation on or near a biomaterial that is on the surface of an implant, medical device, tube, or therapeutic delivery vehicle. Also provided are kits for practicing these methods and the modified biomaterials.
