Single- or dual-bladder devices for automated delivery of remote ischemic conditioning treatment via partial limb occlusion involve various methods of operating the cuff in which partial or full limb occlusion is achieved during the periods of cuff inflation. Achieving clinical benefits of remote ischemic conditioning without extended cessation of limb blood flow are advantageous due to lower required cuff pressure and reduced risk of clot formation in the limb vasculature.
