KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
发明人:
PARK, Young Woo,박영우,JO, Ki Won,조기원,JO, Sun Jeong,조선정,HYUN, Soon Sil,현순실,PARK, Jae Eun,박재은,YOO, Seok Ho,유석호,JANG, Myeoung Hee,장명희,KIM, Hye Nan,김혜난,PARK, Chan Woong,박찬웅
申请号:
KRKR2012/010189
公开号:
WO2013/081379A1
申请日:
2012.11.28
申请国别(地区):
WO
年份:
2013
代理人:
摘要:
The present invention relates to a drug conjugate comprising a cytotoxic drug linked to a c-Met specific human antibody. More specifically, the present invention relates to: a drug conjugate comprising a cytotoxic drug linked to a c-Met specific human antibody a pharmaceutical composition for cancer treatment comprising the drug conjugate and a cancer treatment method comprising a step in which the drug conjugate or pharmaceutical composition is administered to an individual.La présente invention concerne un conjugué médicamenteux comprenant un médicament cytotoxique lié à un anticorps humain spécifique de c-Met. La présente invention concerne, plus précisément, un conjugué médicamenteux comprenant un médicament cytotoxique lié à un anticorps humain spécifique de c-Met une composition pharmaceutique utilisable en vue du traitement du cancer et contenant ledit conjugué médicamenteux et une méthode de traitement du cancer comprenant une étape consistant à administrer ledit conjugué médicamenteux ou ladite composition pharmaceutique à un individu.본 발명은 c-Met에 특이적인 인간항체에 세포독성 약물이 접합된 약물 복합체에 관한 것으로, 구체적으로 c-Met에 특이적인 인간항체에 세포독성 약물이 접합된 약물 복합체, 상기 약물 복합체를 포함하는 암 치료용 약학적 조성물 및 상기 약물 복합체 또는 약학적 조성물을 개체에 투여하는 단계를 포함하는 암 치료 방법에 관한 것이다.