A clip device (1612) for hemostasis includes a clip having a plurality of arms (1640,1650) each having a proximal end and a distal end, wherein each of the arms are spacedapart from each other when the clip is in an open position and adjacent to each otherwhen the clip is in a closed position. At least one lumen (1643, 1653) is disposedwithin a first of the plurality of arms and spans from the proximal end to the distalend of the first arm. At least one outlet bore is formed in the distal end of the firstarm. In use, the distal ends of the plurality of arms are adapted to engage tissuein the closed position, and a sclerosing agent is adapted to be delivered to tissuevia the lumen and an outlet bore formed in the first arm. Such technique facilitatestreatment of the underlying bleeding using a combination of mechanical and sclerotherapyapproaches.