David J. Witter,Tesfaye Biftu,Purakkattle Biju,Stephane L. Bogen,Qingmei Hong,Chunhui Huang,Xianhai Huang,Bing Li,Min K. Park,David L. Sloman
申请号:
US15769414
公开号:
US10399972B2
申请日:
2016.10.25
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention is directed to tricyclic compounds of formula (I), (Ia) or (Ib) which are inhibitors of one or more mutant IDH enzymes. The present invention is also directed to uses of these tricyclic compounds in the potential treatment or prevention of cancers in which one or more mutant IDH enzymes are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such cancers.