Marion Hitchcock,Ingo Hartung,Florian Pühler,Gerhard Siemeister,Roland Neuhaus
申请号:
US13502545
公开号:
US20120263714A1
申请日:
2010.10.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to substituted halophenoxybenzamide derivative compounds of general formula (I) in which R1, R2, R3, R3a, R4, R5, R6, Ra, Rb, Rc, and X are as defined in the claims, to methods of preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.