A unitary molded polymer histological specimen cassette includes a base defining a compartment, a lid, and a hinge connecting the lid to the base and enabling the lid to move between an open position and a closed position with respect to the base. The lid and base are configured to form a fulcrum and apply sufficient tension to the hinge to fracture the hinge when the lid is moved from the open position to the closed position. Another embodiment of the cassette includes a panel extending from the base and having a print-receptive front surface, a rear surface and a first thickness. A plurality of spaced apart support walls extend between and are integrally molded with the base and the rear surface of the panel to support the panel with respect to the base. The cassette includes a sufficient number of support walls at spaced-apart positions to provide the panel with sufficient rigidity to enable printing on the print-receptive surface. All of the support walls have a substantially equal second thickness that is less than the first thickness of the panel, and the second thickness is a thickness with respect to the first thickness that causes the panel to be sufficiently flat and smooth to enable printing on the print-receptive surface.
