PINK1 C-TERMINAL DOMAIN POLYPEPTIDE AND METHODS USING THE SAME IN CANCER TREATMENT

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专利权人:

发明人:

申请号：

EP16789898.0

公开号：

EP3288963A1

申请日:

2016.05.02

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present disclosure includes a PINK1-C-terminal domain (PINK1-CTD) polypeptide that binds to ERBB tyrosine kinase domain (ERBB-TKD) and therefore impedes ERBB from dimerization and activation. The PINK1-CTD polypeptide inhibits, prevents and/or treats ERBB-expressing cancers. The disclosure demonstrates the anti-tumor function of the PINK1-CTD, which provides a new direction for ERBB-expressing cancer therapy.

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中国工程科技知识中心

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