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Quinuclidine derivative
专利权人:
LTT BIO-PHARMA CO.; LTD.
发明人:
Tohru Mizushima,Yasunobu Yamashita,Naoki Yamakawa
申请号:
US15552623
公开号:
US10155755B2
申请日:
2016.02.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided are a quinuclidine derivative of formula (1) and a medicament comprising the quinuclidine derivative:wherein R1 represents a hydrogen atom, a halogen atom, a lower alkyl group, a haloalkyl group, a lower alkoxy group, or a haloalkoxy group; Y represents —C(C═O)—O—, or —CH2O—; m represents an integer of 1 to 5; Z represents an oxygen atom or a sulfur atom; l represents a number of 0 or 1; n represents an integer of 0 to 4; X− represents an anion; and a substituent of a quinuclidine ring represents a 1,3-bond, or 1,4-bond, provided that when m is 3, l is 1, and n is 0, R1 represents a halogen atom, a lower alkyl group, a haloalkyl group, a lower alkoxy group, or a haloalkoxy group.
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