MODULATORS OF THE FUNCTIONS OF PHASE RECEPTORS AND OTHER PROTEINS

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专利权人:

YEDA RESEARCH AND DEVELOPMENT COMPANY; LTD.

发明人:

BOLDIN, MARK,GONCHAROV, TANYA,WALLACH, DAVID,GOLTSEV, YURY

申请号：

DK08018971

公开号：

DK2042509T3

申请日:

1996.06.14

申请国别(地区):

DK

年份:

2013

代理人:

摘要：

The present invention provides proteins capable of modulating or mediating the FAS receptor ligand or TNF effect on cells carrying FAS receptor or p55 receptor by binding or interacting with MORT-1 protein, which in turn binds to the intracellular domain of the FAS receptor or to another protein TRADD which binds to the p55 receptor. In addition, peptide inhibitors which interfere with the proteolytic activity of MORT-1-binding proteins having proteolytic activity are provided as well as a method of designing them.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/