The prevent invention provides an atomizing system and device having a single authentication mechanism. The system includes at least one atomizing drug container and an atomizing device. The at least one atomized medicine container associates with an authentication code carrier and contains the atomized medicine. The atomizing device includes an atomizing module, a first power module, a control unit, an antenna module and an authentication module. The control unit controls the first power module to output the first driving voltage to directly drive the atomizing module. The antenna module is used for transmitting and receiving signals, and the authentication module is configured to perform an authentication operation associated with the authentication code carrier to determine the authenticity of the at least one atomized medicine container or the atomized medicine and to generate an authentication result signal correspondingly. The control unit determines whether to control the first power module to output the first driving voltage according to the authentication result signal.本發明公開一種具有單認證機制的霧化系統及裝置,此系統包括至少一霧化藥品容器及霧化裝置。至少一霧化藥品容器關聯於認證碼載體且容置有霧化藥品。霧化裝置包括霧化模組、第一電源模組、控制單元、天線模組及認證模組。控制單元控制第一電源模組輸出第一驅動電壓,以直接驅動霧化模組。天線模組用於收發訊號,認證模組經配置以進行與認證碼載體相關的認證操作,以判定至少一霧化藥品容器或霧化藥品的真偽,並對應產生認證結果訊號。其中,控制單元根據認證結果訊號決定是否控制第一電源模組輸出第一驅動電壓。