A dermatome having a head, a neck, and a handle. The head of the dermatome may include a main housing at least partially defining a cavity and a removable member that may be configured to removably engage the main housing. The main housing may include one or more features configured to guide the removable member into alignment with the main housing and/or one or more features configured to engage the removable member. The removable member of the dermatome may be made from a different material than the main housing. The neck may include a first portion and a second portion, where the first portion is made from a different material than the second portion. The dermatome may be configured to connect to one or more of a fluid power source, a battery power source, and a wall power source.