Disclosed is a physiological approach of a penile venous stripping surgical procedure for patients with erectile dysfunction (ED), which mainly contains a revolutionary surgical solution of treating leakage veins for restoring erectile function based on a template of penile tunical and venous anatomy. The method entails a thorough penile venous stripping and then being ligated of one deep dorsal vein and a pair of cavernosal veins whereas two pairs of para-arterial veins are rendered for segmental ligation rather than being stripped closest to the tunica albuginea by using a set of specific instruments under an acupuncture-aided local anesthesia on an ambulatory basis. Although the techniques for handling venous tissues with stripping and then ligation is extraordinarily challenging, this innovative method turns the venous treatment for ED from one that has been abandoned to a curable option.