REES, DAVID CHARLES,大卫 查理斯 利斯,大衛 查理斯 利斯,TREWARTHA, GARY,盖理 特瑞华沙,蓋理 特瑞華沙,VINKOVIC, MLADEN,拉登 温寇维克,拉登 溫寇維克,WYATT, PAUL GRAHAM,保罗 格雷恩 怀尔特,保羅 格雷恩 懷爾特
申请号：
TW095101703
公开号：
TWI455932B
申请日:
2006.01.17
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
The invention provides an acid addition salt of 4-(2,6-dichloro-benzoylamino)- 1H-pyrazole-3-carboxylic acid piperidin-4-ylamide and crystals thereof, the salt being formed with an acid selected from methanesulphonic acid and acetic acid and mixtures thereof.Also provided are the novel uses of salts of 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3- carboxylic acid piperidin-4-ylamide, processes for the preparation of 4-(2,6-dichloro-benzoylamino) -1H-pyrazole-3-carboxylic acid piperidin-4-ylamide and its salts and novel chemical intermediates.本發明提供4-(2,6-二氯-苯甲醯胺基)-1H-吡唑-3-羧酸哌啶-4-基醯胺之酸加成鹽和其結晶,該鹽係與選自甲烷磺酸和乙酸及其混合物之酸形成。也提供4-(2,6-二氯-苯甲醯胺基)-1H-吡唑-3-羧酸哌啶-4-基醯胺之鹽的新穎用途、製備4-(2,6-二氯-苯甲醯胺基)-1H-吡唑-3-羧酸哌啶-4-基醯胺和其鹽之方法及新穎化學中間物。
