GREENLEE, MARK, L. ML,.格林李,WILKENING, ROBERT R,.威爾克寧,APGAR, JAMES J,.阿普加,SPERBECK, DONALD D,.斯珀爾貝克,WILDONGER, KENNETH, JAMES KJ,.維爾登格,MENG, DONGFANG,孟東方,PARKER, DANN L., JR. DL,.帕克,PACOFSKY, GREGORY,
申请号:
HK16102165.7
公开号:
HK1214271A
申请日:
2016.02.25
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
Novel derivatives of enfumafungin are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antifungal agents and/or inhibitors of (l,3)-beta-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs,,as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions.